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![]() "Supralimus" From Darkness to Dawn ... |
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We and others demonstrated that rapamycin inhibits
the proliferation of rodent and human vascular SMCs in vitro and porcine vascular SMCs in vivo by blocking cell cycle progression
at the G1/S transition. The vascular SMCs are based on earlier observations showing that the immunosuppressant activity of
rapamycin linked to its ability to inhibit cell cycle progression in T lymphocytes |
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Sirolimus-Eluting Coronary Stent |
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